The Neurospora circadian clock: simple or complex?
نویسندگان
چکیده
منابع مشابه
GSK modulates the Neurospora circadian clock
Background: The period length of the Neurospora circadian clock is dependent on expression levels of its core transcription factor WCC. Results: Glycogen Synthase Kinase (GSK) forms a complex with the WCC and regulates its abundance. Conclusion: GSK modulates the period length of the circadian clock. Significance: GSK is a novel clock component of Neurospora transducing signals to the core osci...
متن کاملEntrainment of the Neurospora circadian clock.
Neurospora crassa has been systematically investigated for circadian entrainment behavior. Many aspects of synchronization can be investigated in this simple, cellular system, ranging from systematic entrainment and drivenness to masking. Clock gene expression during entrainment and entrainment without clock genes suggest that the known transcription/translation feedback loop is not alone respo...
متن کاملPosttranslational control of the Neurospora circadian clock.
The eukaryotic circadian clocks are composed of autoregulatory circadian negative feedback loops that include both positive and negative elements. Investigations of the Neurospora circadian clock system have elucidated many of the basic mechanisms that underlie circadian rhythms, including negative feedback and light and temperature entrainment common to all eukaryotic clocks. The conservation ...
متن کاملNucleosome dynamics regulate Neurospora circadian clock.
Organisms utilize the circadian clock system to adapt to the predictable changes from day;night cycles. The circadian oscillator is based on transcription feedback loops in which alternate cycles of transcription activation and repression generate rhythmic accumulation of clock gene products and their downstream effectors of physiology. There is growing evidence that dynamic histone accumulatio...
متن کاملSimple Sequence Repeats Provide a Substrate for Phenotypic Variation in the Neurospora crassa Circadian Clock
BACKGROUND WHITE COLLAR-1 (WC-1) mediates interactions between the circadian clock and the environment by acting as both a core clock component and as a blue light photoreceptor in Neurospora crassa. Loss of the amino-terminal polyglutamine (NpolyQ) domain in WC-1 results in an arrhythmic circadian clock; this data is consistent with this simple sequence repeat (SSR) being essential for clock f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences
سال: 2001
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2001.0968